The driving distance from St. Louis to Chicago is 295 miles
or 475 kilometers
This is a medium length road trip, starting from Saint Louis, MO and arriving at your destination of Chicago, IL with a total driving time of 4 hours, 56 minutes
If you just want to know how far it is between St. Louis and Chicago, the straight line distance is 260 miles
or 418 kilometers
If you are a pilot flying a private plane, you can fly straight from Saint Louis, MO to Chicago, IL for a total flight time of 45 minutes
Book a flight:
If you're a traveler planning a trip and you want to book a commercial flight, you can try searching for flights between STL and ORD.