The driving distance from Orlando to Key West is 394 miles
or 634 kilometers
This is a long road trip, starting from Orlando, FL and arriving at your destination of Key West, FL with a total driving time of 6 hours, 51 minutes
If you just want to know how far it is between Orlando and Key West, the straight line distance is 275 miles
or 443 kilometers
If you are a pilot flying a private plane, you can fly straight from Orlando, FL to Key West, FL for a total flight time of 48 minutes
Book a flight:
If you're a traveler planning a trip and you want to book a commercial flight, you can try searching for flights between MCO and EYW.