Downtown is a great option for places to stay in Santiago. The ultrasleek modern metro will take you out into other areas if that's your idea of daytime fun, but in the meantime, you'll have quick access to museums, people watching, good food and both Cerro Santa Lucia and Cerro San Cristobal (the two hills, small and large that overlook the city) when you stay within Santiago's central district bordered by Plaza Italia to the east (metro Baquedano). Hostels tend to cluster in Barrio Brasil and Bellavista, while hotels show up in Bellas Artes and Cerro Santa Lucía which are neighborhoods that are easy to get to and quite safe.
Av. Libertador Bernardo O'Higgins 136
One of Santiago's best-known hotels in the heart of downtown... read more
Monjitas 506, Barrio Bellas Artes
Andes Hostel is located in an older, but well-renovated building across from the Bellas Artes metro and just a short walk from the city's main café strip. It has small but suitable clean rooms to suit families, couples and single backpackers... read more
Baron Pierre De Coubertin 62
Avenida Bernardo O'Higgins 853
A 1970s hotel in the centre of Santiago... read more