The driving distance from Chicago to St. Louis is 295 miles
or 475 kilometers
This is a medium length road trip, starting from Chicago, IL and arriving at your destination of Saint Louis, MO with a total driving time of 4 hours, 57 minutes
If you just want to know how far it is between Chicago and St. Louis, the straight line distance is 260 miles
or 418 kilometers
If you are a pilot flying a private plane, you can fly straight from Chicago, IL to Saint Louis, MO for a total flight time of 47 minutes
Book a flight:
If you're a traveler planning a trip and you want to book a commercial flight, you can try searching for flights between ORD and STL.