The driving distance from Greenville to Charleston (SC) is 326 miles
or 525 kilometers
This is a medium length road trip, starting from Greenville, NC and arriving at your destination of Charleston, SC with a total driving time of 4 hours, 44 minutes
If you just want to know how far it is between Greenville and Charleston (SC), the straight line distance is 244 miles
or 393 kilometers
If you are a pilot flying a private plane, you can fly straight from Greenville, NC to Charleston, SC for a total flight time of 59 minutes
Get more details to plan a trip from
Greenville to Charleston (SC).