The driving distance from Knoxville to Charleston (SC) is 373 miles
or 600 kilometers
This is a long road trip, starting from Knoxville, TN and arriving at your destination of Charleston, SC with a total driving time of 6 hours, 4 minutes
If you just want to know how far it is between Knoxville and Charleston (SC), the straight line distance is 316 miles
or 509 kilometers
If you are a pilot flying a private plane, you can fly straight from Knoxville, TN to Charleston, SC for a total flight time of 1 hour, 8 minutes
Get more details to plan a trip from
Knoxville to Charleston (SC).