The driving distance from Tampa/St. Petersburg to Key West is 422 miles
or 679 kilometers
This is a long road trip, starting from Tampa, FL and arriving at your destination of Key West, FL with a total driving time of 7 hours, 17 minutes
If you just want to know how far it is between Tampa and Key West, the straight line distance is 237 miles
or 382 kilometers
If you are a pilot flying a private plane, you can fly straight from Tampa, FL to Key West, FL for a total flight time of 42 minutes
Get more details to plan a trip from
Tampa/St. Petersburg to Key West.