The driving distance from Odessa to San Antonio is 342 miles
or 550 kilometers
This is a medium length road trip, starting from Odessa, TX and arriving at your destination of San Antonio, TX with a total driving time of 4 hours, 59 minutes
If you just want to know how far it is between Odessa and San Antonio, the straight line distance is 285 miles
or 458 kilometers
If you are a pilot flying a private plane, you can fly straight from Odessa, TX to San Antonio, TX for a total flight time of 1 hour, 4 minutes
Get more details to plan a trip from
Odessa to San Antonio.