The driving distance from Louisville to St. Louis is 260 miles
or 418 kilometers
This is a medium length road trip, starting from Louisville, KY and arriving at your destination of Saint Louis, MO with a total driving time of 4 hours, 7 minutes
If you just want to know how far it is between Louisville and St. Louis, the straight line distance is 242 miles
or 390 kilometers
If you are a pilot flying a private plane, you can fly straight from Louisville, KY to Saint Louis, MO for a total flight time of 47 minutes
Get more details to plan a trip from
Louisville to St. Louis.